

Urea
Indications
Urea 41% Cream is indicated for the treatment of dry, rough, cracked, and callused skin, as well as diseased or damaged nails. For external use only. Not for ophthalmic use.
Patient Assistance
Eligible for Patient Assistance
Learn more about copay support for your patients.
View Patient Assistance Details →Key Benefits
Deep Hydration
41% urea helps soften and hydrate dry skin.
Exfoliating Action
Smooths rough, cracked, and callused skin.
Nail Support
Softens diseased or damaged nails.
Prescription Strength
High-potency formulation dispensed by prescription.
Quality You Can Trust
Manufactured to Oncora's quality standards.
Dosage & Administration
Apply Urea 41% Cream to affected area(s) twice per day, or as directed by your physician. Rub until completely absorbed. Apply to diseased or damaged nail(s) twice per day, or as directed by a physician. Avoid contact with eyes, lips, or mucous membranes.
Storage
Store at 20 to 25°C (68–77°F) [see USP Controlled Room Temperature]. Protect from freezing and excessive heat. Keep container tightly closed. Keep out of reach of children.
Product Details
| NDC | 85477-306-27 |
| Strength | 41% |
| Dosage Form | Topical Cream |
| Package Size | 8 oz (227 g) |
| Availability | Rx Only |
Frequently Asked Questions
What is Urea used for?
Urea 41% Cream is indicated for the treatment of dry, rough, cracked, and callused skin, as well as diseased or damaged nails. For external use only. Not for ophthalmic use.
Who is Urea intended for?
Urea is intended for patients needing the treatment of dry, rough, cracked, and callused skin, as well as diseased or damaged, under the direction of a licensed healthcare provider. It is dispensed by prescription only.
How should Urea be used?
Apply Urea 41% Cream to affected area(s) twice per day, or as directed by your physician. Rub until completely absorbed. Apply to diseased or damaged nail(s) twice per day, or as directed by a physician. Avoid contact with eyes, lips, or mucous membranes.
What strength and package size does Urea come in?
Urea is supplied as 41% in a topical cream, 8 oz (227 g), NDC 85477-306-27.
Does Urea require a prescription?
Yes — Urea is Rx Only and must be prescribed by a licensed healthcare provider and dispensed by a licensed pharmacy.
How is Urea stored and shipped?
Store at 20 to 25°C (68–77°F) [see USP Controlled Room Temperature]. Protect from freezing and excessive heat. Keep container tightly closed. Keep out of reach of children. Urea ships from Oncora Pharma's Dallas, TX distribution center to licensed pharmacies and wholesalers.
What safety information applies to Urea?
For external use only; avoid contact with the eyes. Do not use if you are allergic to any of the ingredients, and keep out of reach of children. Stop use and contact a healthcare provider if irritation develops or symptoms persist.
Is copay assistance available for Urea?
Eligible patients may pay as little as $0, with the Oncora copay card covering up to $75 per prescription. Restrictions and eligibility requirements apply — see our Patient Assistance page for details.
How can a pharmacy order Urea?
Licensed pharmacies and wholesalers can order Urea (NDC 85477-306-27) through Oncora Pharma. Contact customerservice@oncorapharma.com or use the Partner Application to set up an account.
Explore More Topicals by Indication
Urea is for dry, rough, cracked, and callused skin for the treatment of dry, rough, cracked, and callused skin, as well as diseased or damaged. Browse the rest of our topicals catalog, or view a related indication below.
- Lidocaine 4% Patch™ — topical anesthetic — skin protectant for relief from pain and itching associated with minor burns, sunburn, minor cuts, scrapes
- Lidovara™ — topical anesthetic — fast-acting relief for Lidovara is a topical anesthetic gel containing 2
- Collavera™ — topical anesthetic gel for minor skin irritations and discomfort, with the added soothing and hydrating benefits of
- Topicaine Ultra™ — effective topical anesthetic for targeted skin relief for fast-acting, temporary relief of pain and discomfort associated with minor skin
- Evara™ — for dry, rough, cracked, and callused skin for heal thickened, rough, and dry skin
- Hydralyn™ — topical corticosteroid therapy for Prescription topical hydrocortisone 2% gel in a convenient pump-top bottle for




